Territory: Keystone including Philadelphia and New Jersey.

Natera is seeking an experienced Clinical Oncology Specialist (COS) to join our specialized Genitourinary (GU) Oncology sales team. This high-impact, tumor-specific role will focus on driving adoption and growth of Signatera™, Natera's personalized, tumor-informed molecular residual disease (MRD) test, across the GU Oncology landscape.

Signatera is a circulating tumor DNA (ctDNA) assay designed to detect molecular residual disease and monitor disease recurrence. Across GU cancers, including bladder, renal cell carcinoma, and testicular cancers, Signatera provides highly specific molecular insights that can help clinicians assess recurrence risk, monitor disease status, and inform individualized patient management strategies.

The Clinical Oncology Specialist will serve as a strategic field partner and key representative of Natera Oncology, developing relationships with Key Opinion Leaders (KOLs) and healthcare providers across academic medical centers, integrated delivery networks, hospital systems, and select community oncology practices.

This position will have a primary focus on Urologic Oncology, with key call points including Urologic Oncologists, GU Surgical Oncologists, Radiation Oncologists, Medical Oncologists, Pathologists, and other healthcare providers involved in the diagnosis, treatment, and ongoing management of patients with genitourinary cancers.

Primary Responsibilities

• Develop and execute strategic territory business plans to drive Signatera adoption, achieve sales objectives, and maximize market opportunities.
• Build and strengthen relationships with Urologic Oncologists, GU Surgical Oncologists, Medical Oncologists, Radiation Oncologists, Pathologists, and other key stakeholders across the GU Oncology continuum of care.
• Drive new account acquisition, expand existing partnerships, and identify growth opportunities within academic medical centers, hospital systems, leading urology practices, and community oncology networks.
• Educate healthcare providers on Signatera's clinical applications, supporting evidence, and value in the management of GU cancers, including bladder, kidney, and testicular cancers.
• Develop relationships with Key Opinion Leaders (KOLs) specializing in GU Oncology, particularly within major academic medical centers and leading urology and oncology practices.
• Establish expertise in Natera's molecular diagnostics technology, clinical evidence, product offerings, and competitive landscape.
• Collaborate closely with Natera's Core Oncology Sales team and cross-functional partners to align account strategies and maximize commercial effectiveness.
• Identify opportunities to expand Signatera adoption through physician education, strategic account development, and multidisciplinary care team engagement.
• Navigate complex healthcare systems, reimbursement processes, and institutional requirements to support successful product adoption.
• Partner with internal teams to resolve operational challenges, support account needs, and ensure a positive customer experience.
• Collaborate with Medical Affairs to support appropriate scientific engagement and KOL development in accordance with company policies.
• Support the development of institutional care pathways, account-level workflows, and EMR integrations to facilitate testing adoption.
• Monitor market trends, competitive dynamics, and evolving clinical evidence in GU Oncology to identify opportunities for territory growth.
• Execute sales and marketing initiatives aligned with regional and national Oncology objectives.

Qualifications

• Bachelor's degree required.
• Minimum of 5 years of demonstrated sales success within Oncology, Urology, Urologic Oncology, Medical Devices, Molecular Diagnostics, Clinical Diagnostics, or the diagnostic laboratory industry.
• Experience calling on Urologic Oncologists, GU Surgical Oncologists, Urologists, or other GU Oncology specialists strongly preferred.
• Experience selling into academic medical centers, integrated healthcare systems, hospital networks, and/or community oncology practices preferred.
• Demonstrated track record of achieving or exceeding sales goals, developing new markets, and growing complex territories.
• Experience with molecular diagnostics, precision oncology, or innovative medical technologies preferred.
• Ability to travel 50–75%, including overnight travel as required.

Knowledge, Skills, and Abilities

• Strong understanding of the GU Oncology landscape, including key physician specialties, treatment pathways, and multidisciplinary care models.
• Knowledge of molecular diagnostics, ctDNA, MRD testing, and precision oncology preferred.
• Exceptional communication, presentation, relationship-building, and consultative selling skills.
• Strong business acumen with the ability to identify market opportunities, develop strategic account plans, and execute territory growth initiatives.
• Ability to establish and maintain trusted relationships with Key Opinion Leaders, physician stakeholders, and healthcare executives.
• Ability to effectively navigate complex healthcare systems, reimbursement environments, and institutional decision-making processes.
• Collaborative approach to working with cross-functional teams, including Core Oncology Sales, Marketing, Medical Affairs, and internal support functions.
• Strong organizational, analytical, and problem-solving skills.
• Self-motivated, results-oriented, and adaptable to a fast-paced, evolving healthcare environment.
• Commitment to ethical business practices, clinical integrity, and improving patient care.

Why Join Natera?

Join Natera and play a meaningful role in advancing precision oncology for patients with genitourinary cancers.

As a Clinical Oncology Specialist, you will have the opportunity to drive adoption of innovative MRD technology, establish relationships with leading Urologic Oncologists and cancer centers, and expand access to personalized molecular testing.

This is an opportunity to help shape the future of GU Oncology while contributing to Natera's continued growth and mission to transform disease management through innovative diagnostics.

Compensation & Benefits

The total on-target earnings (OTE) package includes:

• Competitive base salary with uncapped quarterly commissions.
• Car allowance program.
• Restricted Stock Units (RSUs).
• Comprehensive benefits package supporting health, wellness, and career growth.