The Opportunity

Amylyx Pharmaceuticals is seeking an experienced Medical Affairs Scientific Communications & Review Consultant to support scientific communications and promotional medical review, with a primary focus on PBH and the opportunity to contribute across the broader pipeline as business needs evolve.

This hands-on role combines scientific content development, clinical data interpretation, promotional medical review, and oversight of external medical communications agencies. The consultant will work independently and collaborate with cross-functional stakeholders to deliver accurate, balanced, and consistent scientific materials. This contracted engagement is anticipated to run from January 2027 through June 2027.

Responsibilities

Promotional Medical Review

• Serve as a primary Medical Affairs reviewer of promotional materials through the Medical, Legal, and Regulatory (MLR) review process.
• Evaluate promotional claims, clinical data presentations, references, and supporting evidence for scientific accuracy, balance, and consistency with approved product labeling; identify unsupported claims and potentially misleading interpretations.
• Provide clear, actionable medical review comments and collaborate with Commercial, Regulatory, Legal, and Medical Affairs stakeholders to resolve scientific questions.
• Partner with therapeutic area Medical Affairs leads on complex scientific issues and escalate matters requiring additional medical judgment.

Scientific Communications

• Independently develop and critically review scientific materials, including abstracts, posters, oral presentations, manuscripts, slide decks, and medical education resources; verify data, references, tables, figures, and scientific claims.
• Critically evaluate clinical trial data and scientific literature, translating findings into clear scientific narratives with consistent interpretation and presentation of the evidence.
• Support the execution of scientific communications plans, including congress and publication activities.
• Collaborate with Medical Affairs therapeutic area leads, biostatistics, clinical development, and other stakeholders to ensure scientific accuracy and alignment with evolving Medical Affairs priorities.
• Provide scientific direction and oversight to external medical communications agencies, including reviewing deliverables, providing substantive feedback, and ensuring high-quality execution.

Required Qualifications

• Advanced scientific or clinical degree (PharmD, PhD, MD, or equivalent).
• Approximately 5–8+ years of relevant experience in pharmaceutical or biotechnology Medical Affairs, scientific communications, or related functions.
• Demonstrated experience performing medical review of pharmaceutical promotional materials.
• Strong experience developing scientific communications, including abstracts, posters, presentations, and/or peer-reviewed manuscripts.
• Demonstrated ability to independently interpret clinical trial data and critically evaluate scientific evidence.
• Excellent scientific writing, analytical, and communication skills, with strong attention to detail and commitment to scientific accuracy and quality.
• Experience collaborating with and providing scientific oversight to external medical communications agencies.
• Ability to work independently, collaborate cross-functionally, manage competing priorities, and deliver high-quality work within established timelines.

Preferred Qualifications

• Experience supporting Medical Affairs activities during prelaunch or commercial launch.
• Experience in endocrinology, metabolic diseases, neuroscience, or rare diseases.
• Familiarity with pharmaceutical promotional review requirements and relevant FDA regulations and guidance.
• Experience working in a small or growing biotechnology organization.
• Demonstrated ability to contribute to multiple scientific projects across therapeutic areas.

Work Location and Conditions

• At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska and Hawaii.
• Occasional travel may be requested for business meetings or other Medical Affairs activities. Actual hours may vary based on project requirements and business needs.
• You must have access to work in a setting that meets all requirements of the role (including privacy, reliable internet access, phone, ability to communication via video conference, etc.) at your remote location.
• The engagement may be extended, and the consultant may be considered for future full-time opportunities, subject to business needs, performance, and applicable company policies.