Primary Responsibilities: Develop and apply QQQ and high-resolution LC/MS approaches to characterize PK, biotransformation, and biodistribution of therapeutic proteins and new drug modalities in pre-clinical animal models. Serve as the bioanalytical representative with project teams to achieve project milestones. Prioritize workload and mentor staff scientists within a broad field bioanalytical team. Job Requirements: M.S. in biochemistry/molecular biology, bioengineering, biology, pharmacology, chemistry, or equivalent field and 6+ years of work experience (or B.S. with 9+ years). Experience developing and implementing orbitrap mass spectrometry applications to investigate ADME properties of therapeutic proteins and new modalities (Large Molecules). Experience with wet biochemistry and sample preparation techniques for isolating biotherapeutics from biological matrices. Authorization to work in the United States full-time; Lilly will not provide support/sponsorship for work authorization/visas (including listed visa types). Preferred Qualifications: Expertise in bioanalysis of siRNA or Antibody-Oligonucleotide Conjugates (AOC); assessing PK, efficacy, and toxicology profiles in preclinical models and presenting data. Knowledge of ADME principles of biotherapeutic drugs; proteomics methods and workflows (DDA, nano-LC, DIA, etc.), plus automation/higher throughput and biotransformation software tools. Excellent written and verbal communication; strong work planning, record keeping, and data analysis skills. Benefits: Anticipated wage: $65,250 - $193,600; full-time employees may be eligible for a company bonus; comprehensive benefit program (e.g., 401(k), pension, vacation, medical/dental/vision, life insurance, time off/leave, well-being benefits). #J-18808-Ljbffr
Principal Scientist, Bioanalytical Research
SCORPION THERAPEUTICS
indianapolis, indianapolis
Published 4 days ago
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