Position Overview Verve Therapeutics, a wholly owned subsidiary of Eli Lilly & Company within Lilly Research Labs, is a clinical‑stage genetic medicines company that focuses on developing gene‑editing therapies for cardiovascular disease. This role is within the Analytical Development group, responsible for creating and optimizing analytical methods for raw materials, RNA drug substances, and LNP products across development stages. Responsibilities Develop, optimize, qualify, and execute analytical methods for release, stability testing, product characterization, high‑throughput analysis, and complex raw material analysis. Collect, process, and analyze experimental data using HPLC, UHPLC, capillary electrophoresis, LCMS, and other instrumental techniques. Maintain accurate documentation in electronic laboratory notebooks. Review, interpret, and present analytical data to internal and cross‑functional teams. Author, review, and revise technical source documents for phase‑appropriate comparability. Provide technical oversight for analytical and QC investigations as needed. Collaborate with process development, quality, and analytical research teams. Train and mentor junior team members. Basic Requirements MS in analytical chemistry, biochemistry, biophysics, or a related field with 3+ years in the biotech or biopharmaceutical industry, or BS with 5+ years of experience in gene therapy. 2+ years of experience with LC, GC, and CE instruments. Experience in development, optimization, qualification, and transfer of methods to internal or external QC environments. Authorized to work in the United States on a full‑time basis. Lilly does not sponsor work authorization or visas. Additional Skills / Preferences Hands‑on experience with biophysical assays (IP‑RP, IEX, SEC), capillary electrophoresis, DLS, GC, and plate‑based assays. Strong background in analytical methodologies for gRNA, mRNA, and LNPs. Proficiency in method development, qualification, validation, and implementation from non‑GxP to GMP environments. Familiarity with ICH regulations and multi‑compendial guidelines related to method validation. Proactive, creative, and positive attitude with effective oral and written communication skills. Compensation & Benefits Expected salary range: $71,250 – $187,000 (full‑time equivalent). Employees are eligible for a company bonus based on performance, a 401(k) plan, pension, paid vacation, medical, dental, vision, and prescription drug benefits, flexible spending accounts for health and dependent care, life insurance, sick leave, and well‑being programs (e.g., employee assistance and fitness benefits).Compensation can vary with education, experience, and location. EEO Statement Lilly is a proud EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status. Qualified applicants may request accommodations through our workplace accommodation form. #J-18808-Ljbffr
Sr. Scientist, Analytical Cmc
ELI LILLY AND COMPANY
boston, boston
Published 4 days ago
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