The Senior Clinical Director (Senior Principal Scientist) has primary responsibility for planning and directing clinical research activities involving new or marketed medicines in the Late Stage Oncology therapy area. Our company’s oncology medicines span all phases of development, from pre‑clinical to post‑licensure. The Senior Clinical Director may manage the entire clinical development cycle for assigned studies, including study design, initiation, execution, monitoring, analysis, regulatory reporting, and publication. Responsibilities Evaluate pre‑clinical and translational work to generate early clinical development plans and IND applications. Develop clinical development strategies for investigational or marketed renal cell carcinoma (RCC) drugs. Plan clinical trials—designing studies and collaborating on operational plans. Provide medical oversight and overall conduct of ongoing or new clinical trials. Analyze and summarize clinical findings to support safety and efficacy decisions and new drug applications. Participate in internal and joint research project teams relevant to the development of new and marketed compounds. Support business development assessments of external opportunities. Actively engage with other functional areas (commercialization, regulatory affairs, statistics, manufacturing) to manage clinical development projects. Assist senior executives in informing the progress of studies and competitive developments. Provide expert scientific opinion internally and externally on relevant questions. Maintain a strong scientific knowledge base by staying current on research developments, identifying investigators, establishing partnerships, and attending scientific meetings. Author detailed development documents, presentations, budgets, and position papers for internal and external audiences. Facilitate collaborations with external researchers worldwide. Travel about 20% of the time to manage future or ongoing clinical research projects. Education M.D. or M.D./Ph.D. Required Experience and Skills Experience in industry or as senior faculty in academia. Minimum 3 years of clinical medicine experience. Minimum 3 years of industry experience in drug development or biomedical research experience in academia. Demonstrated success in overseeing clinical studies and protocols. Demonstrated record of scientific scholarship and achievement. Proven track record in clinical medicine and a background in biomedical research. Strong interpersonal skills and ability to function in a team environment. Ability to provide expert opinion on relevant scientific questions. Preferred Experience and Skills Board Certified or Eligible in Oncology or a related discipline. Experience in GU malignancies. Prior specific experience in clinical research and prior publication. Required Skills Clinical Development Clinical Judgment Clinical Medicine Clinical Research Management Clinical Sciences Clinical Trial Development Clinical Trials Drug Development Intellectual Curiosity Oncology Oncology Research Pharmaceutical Development Strategic Planning Salary and Benefits Salary range: $282,200.00 – $444,200.00. The successful candidate will be eligible for annual bonus and long‑term incentive, if applicable. Benefits include medical, dental, vision, healthcare and other insurance for employee and family, retirement benefits (401(k)), paid holidays, vacation, compassionate and sick days. More information about benefits is available at the company compensation portal. Equal Employment Opportunity Statement As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. Location Requirement SanFrancisco. Only residents of SanFrancisco are considered for this position. #J-18808-Ljbffr